CHOLESTEROL, CORONARY HEART DISEASE (CHD) &
BioZama



The common perception that fat and cholesterol are uniformly bad for the cardiovascular system is being questioned by a host of current studies. Elevated cholesterol levels are associated with heart disease in the United States, Finland, the Netherlands, Italy, Greece, Croatia, Serbia (formerly part of Yugoslavia), and Japan. However, in certain countries, they may pose more of a threat than others. For example some studies show that while cholesterol levels of 210 mg/dL correspond to a 5 percent increase in the death rate from heart disease in Japan and Mediterranean Europe, it translates to a 10 percent increase in the death rate in central Europe, 12 percent in the United States, and 15 percent in Northern Europe. Men with a cholesterol level generally considered safe (190 mg/dL) are twice as likely to die of heart disease in Northern Europe than in the Mediterranean. It has become apparent that other aspects of the diet, besides cholesterol, are important for protection from cardiovascular disease. Compared with the Northern European and US diets, the Mediterranean diet contains less meat, more fish, fresh fruits, nuts and fresh vegetables. The fatty acids consumed in Northern Europe and the United States are pre-dominantly saturated but in the Mediterranean predominantly monounsaturated. Intake of the antioxidant vitamins beta-carotene and alpha-tocopherol (Vitamin E) is highest in the Mediterranean. Flavonoids, the most powerful of which is 'quercitin', intake is twice as high in the Mediterranean as in Northern Europe and the United States, and is highest in Japan.

The BioZama formulation (Pat. Pending.) contains phytochemicals, i.e. flavonoids and polyphenols. It has been shown that flavonoids, high in quercitin and polyphenolic compounds, with powerful antioxidant properties, protect against CHD (Coronary Heart Disease).
The way that cholesterol becomes harmful to our health is much more complex than once thought. In fact, it turns out that it is only when certain conditions are present that cholesterol can begin to clog up the arteries and lead to heart disease.

Cholesterol is divided into two types: Low Density Lipoproteins and High Density Lipoproteins, referred to as LDL and HDL, respectively. Oxidized LDL stimulates macrophages (which are the immune system cells that capture and trap foreign cells and particles in the blood), which accumulate cholesterol, and foam cells are formed (which are cells that try to clean out the area). It is toxic to cells of the arterial wall and it stimulates inflammatory and clotting processes. All major cells in the arterial wall, including endothelial (1) cells, smooth muscle cells and macrophages, can oxidize LDL!

Macrophage-mediated oxidation of LDL is probably a hallmark in early atherosclerosis (2)
The LDL oxidative state is elevated by increased ratio of poly/mono unsaturated fatty acids, and it is reduced by polyphenolic substances, which are phytochemicals with 100 times the antioxidant power of Vit. C.

The BioZama are an excellent source of dietary polyphenols and flavonoids.
Have a blood test done before and after taking BioZama for a 3-month period. Your Physician may find an improvement in your Lipid Profile.





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